Место работы автора, адрес/электронная почта: Республиканская больница N 2 - Центр экстренной медицинской помощи, Неврологический отдел ; 677000, г. Якутск, ул. П. Алексеева, 83 "а" ; http://rb2cemp.ru
Ответственность: Оконешникова Людмила Тимофеевна (Составитель), Горохова Надежда Юрьевна (Составитель), Николаева Татьяна Яковлевна (Составитель), Конникова Эдилия Эдуардовна (Прочие), Голикова Полина Иннокентьевна (Прочие)
Издательство: Адверти
Год выпуска: 2016
Количество страниц: 20 с.
Рассеянный склероз и беременность : методическое пособие для пациентов, врачей / Министерство здравоохранения Республики Саха (Якутия) [и др.] ; составители: Л. Т. Оконешникова, Н. Ю. Горохова, Т. Я. Николаева. - Якутск : Адверти, 2016. - 16 с.
Количество страниц: 4 с.
Особенности цитокинового статуса и интратекальный синтез олиго-клональных IGG у больных вилюйским энцефаломиелитом и рассеянным склерозом / Т. М. Сивцева, Р. И. Чемезова, В. А. Владимирцев [и другие ] // Якутский медицинский журнал. – 2011. – N 4 (36). – С. 27-29.
Количество страниц: 4 с.
The diagnostics of chronic inflammatory demyelinating polyneuropathy (CIDP) is a difficult task, as the classical diagnostic criteria are not specific enough, the clinical picture of the disease is polymorphic, and there are no reliable biomarkers of this disease. The diagnosis is based on a characteristic clinical picture and is confirmed by the detection of the demyelinating type of peripheral nerve damage in electroneuromyography or nerve biopsy, as well as excluding other diseases that may be accompanied by a similar clinical picture. Currently, the importance of lumbar puncture in the diagnostics of CIDP is being questioned, since not all patients, especially at the outpatient level, are undergoing this procedure, and typical protein-cell dissociation in approximately 40 % of patients may not be detected, especially in the first 2 weeks from the moment of the disease. Therefore, in the diagnostics of CIDP, especially its atypical forms, they introduce such methods as computerized pallestesiometry, ultrasound examination of peripheral vessels, magnetic resonance imaging of the nerve roots, and blood testing for antibodies to viruses tropic to nervous tissue. The article deals with the clinical case of a CIDP patient, who does not have a typical protein-cell dissociation in CSF, however, other paraclinic data, characteristic of inflammatory polyneuropathies, are manifested
О возможностях параклинических методов исследования в диагностике хронической воспалительной демиелинизирующей полиневропатии: клиническое наблюдение / Т. Е. Попова, А. А. Таппахов, А. Д. Алексеева, Л. Т. Тимофеева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 82-84.
Количество страниц: 6 с.
The problem of autoimmune diseases is relatively young, about 50 years, but despite the short period, it has become the most relevant in modern clinical neurology. A special place among the demyelinating autoimmune disease is neuromyelitis optica. Neuromyelitis optica the second most frequent form of inflammatory, autoimmune, demyelinating disease after multiple sclerosis. In the last decade, the scientific understanding of Devic’s disease has expanded significantly. Neuromyelitis optica refers to rare, demyelinating diseases of the nervous system, while in the literature there is no precise data on the incidence and prevalence of the disease. To date, information about epidemiology is based on the results of individual studies. It is known, that the disease is more often diagnosed among people of Asian descent, in all populations women are more often ill. Neuromyelitis optica, unlike other demyelinating diseases, has a severe progressive course and quickly leads to persistent disability. To date, with the isolation of a specific marker (NMO-IgG), there are opportunities for an accurate diagnosis. This article presents a case of a recurring course of opticoneuromyelitis meeting the known diagnostic criteria, including the determination of aquaporin-4 antibodies of aquaporin 4 in serum. Timely diagnosis of the disease, taking into account some clinical features, using immunological methods (determination of oligoclonal antibodies, determination of the level of aquaporin-4 antibodies), instrumental methods (especially MRI in neuromyelitis optica), timely adequate treatment, will help reduce the likelihood of irreversible neurological deficit
Оптиконейромиелит: клиническое наблюдение / Н. Ю. Горохова, Т. Я. Николаева, Т. Е. Попова, Л. Т. Оконешникова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2018. — N 3 (12). — С. 17-21.